Mesenchymal stem cells; defining the future of regenerative medicine

نویسندگانAsieh Heirani-Tabasi, Marzieh Hassanzadeh, Shabnam Hemmati-Sadeghi, Mina Shahriyari, Mahmood Raeesolmohaddesin
نشریهBlood
شماره صفحات19
نوع مقالهFull Paper
تاریخ انتشار2001
رتبه نشریهISI
نوع نشریهچاپی
کشور محل چاپایران

چکیده مقاله

Cell therapy has been considered as the third pillar of medicine. There are several kinds of cells attracted researchers attention whereas the growing interest in mesenchymal stem cells (MSCs) for regenerative purposes has enabled them to explore the versatile characteristics for regenerative purposes. So far, near about 5000 clinical trials using MSCs, authenticating the clinical applicability of these cells. Their multipotent differentiation and unique immunosuppressive properties have made them ideal candidate in cell therapeutic approaches. Recent advances have been observed in the homing of these cells to enhance their transplantation efficacy. These cells have been proposed as the ideal candidates for cancer therapy and have been engineered for targeted cancer therapy. Their successful applications and responses have termed them the ideal cells for the future of regenerative medicine.